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Using two separate drugs to lose weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the those who go through it you need to err to the side of caution and allow FDA do its job and demand some investigation be done so your public knows the side effects and hazards of the medications before we take them. Keep in mind that drug companies come in business to make money and that they would say almost anything to keep people on their medications. Researchers found out that participants using this drug to get a year, dropped excess weight within four weeks and have kept the extra weight off through the entire 56 weeks with the study. Contrave can be a combination from the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which can be made up of many active ingredient, which may make them far better and safer. Combo-pilling is the newest fad or even better the newest in the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular may be the fact that as of right now there aren't long term prescription weight loss supplements that have been approved by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug also can raise blood pressure and heartrate, and mustn't be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must not used in patients with uncontrolled high blood pressure, in addition to by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients for the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking. The most common side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.